Patient Zero: Day One (2015)

by Christopher
5 minutes read


Patient Zero: Day One: A Frantic Top-Down Infect-Em-Up

Patient Zero: Day One is a frantic top-down infect-em-up that will keep you on the edge of your seat. Run freely around the city, hunting down fleeing victims. You must bite them to survive, but as you infect them, they too will turn, and also need to feed.

The game is set in a city that has been overrun by a zombie infection. You play as Patient Zero, the first person to be infected with the virus. Your goal is to survive as long as possible by infecting as many people as you can.

As you infect more people, you will earn Toxins. Toxins can be spent to unlock and equip mutations that will change how you play. You can also use Toxins to unlock different zombies to play as.

There are a total of 10 mutations that you can unlock. Each mutation gives you a different ability, such as increased speed, strength, or stealth. You can equip up to three mutations at a time.

There are also 10 different zombies that you can unlock. Each zombie has its own unique abilities. For example, the Hulk zombie is very strong, while the Ninja zombie is very stealthy.

As you play the game, you will earn rewards for total lifetime infections. These rewards include new mutations, new zombies, and new Toxin bonuses.


Patient Zero: Day One is a fast-paced and action-packed game. You will need to be constantly moving and attacking in order to survive. The game is played from a top-down perspective, and you can use the WASD keys to move around.

To attack, simply press the spacebar. You can also use the left mouse button to bite victims. When you bite a victim, you will infect them with the virus. The victim will then turn into a zombie and start attacking other people.

You can also use the right mouse button to grab victims. This can be useful for pulling victims towards you or for throwing them into obstacles.


There are a few different strategies that you can use to survive in Patient Zero: Day One. One strategy is to focus on infecting as many people as possible. This will give you a large army of zombies that can help you to take down other players.

Another strategy is to focus on upgrading your mutations. Mutations can give you a significant advantage in combat. For example, the Speed mutation can help you to outrun other players, while the Strength mutation can help you to kill them more quickly.

Finally, you can also focus on unlocking new zombies. Each zombie has its own unique abilities, so you can experiment with different zombies to find the one that best suits your playstyle.


Patient Zero: Day One is a fun and challenging game that will keep you entertained for hours on end. The game is fast-paced and action-packed, and there is a lot of strategy involved. If you are a fan of zombie games, then you should definitely check out Patient Zero: Day One.

Tips for Surviving

Here are a few tips for surviving in Patient Zero: Day One:

  • Stay on the move. The zombies are faster than you, so you need to keep moving in order to avoid being caught.
  • Use your mutations wisely. Mutations can give you a significant advantage in combat. Experiment with different mutations to find the ones that best suit your playstyle.
  • Team up with other players. There is strength in numbers. If you can team up with other players, you will be able to take down more zombies and survive longer.
  • Don’t be afraid to experiment. There is no one right way to play Patient Zero: Day One. Experiment with different strategies and find the one that works best for you.

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